Although there is very little evidence about its short and long-term effects, we do know that it is chemically related to dissociative anaesthetics like ketamine and PCP, and has similar effects.
From anecdotal reports, methoxetamine (MXE) appears to be much stronger than ketamine, so users should take extra care to avoid overdosing by only using small amounts.
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Reportedly, because of its strength, only small pinches (or bumps) of methoxetamine are snorted – and not full lines.
Some people prefer to dissolve it in water or place it under their tongue, where it’s dissolved and taken into the bloodstream, but it can also be swallowed (bombed) or injected.